skip to Main Content

The Use of Transcranial Focused Ultrasound for the Treatment of Neurodegenerative Dementias


Brief Summary:

The purpose of this open label study is to evaluate longer term tolerability and early
efficacy of transcranial ultrasound in the treatment of patients with mild cognitive
impairment or dementia.


Inclusion Criteria:

– CDR stage of at least 0.5 (mild cognitive impairment)

– At least one pathognomic imaging biomarker of a neurodegenerative process.

Exclusion Criteria:

– Cognitive decline clearly related to an acute illness

– Subjects unable to give informed consent

– Subjects with scalp rash or open wounds on the scalp (for example from treatment of
squamous cell cancer)

– Advanced terminal illness

– Advanced kidney, pulmonary, cardiac or liver failure

– Subjects who would not be able to lay down without excessive movement in a calm
environment sufficiently long enough to be able to achieve sleep

– Subjects with major depressive disorder

– Subjects with vascular causes of dementia


  • Neurological Associates of West LA, Santa Monica, California, United States, 90403
Back To Top