A Phase Ib Study of Nivolumab in Patients With Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
Sponsor:National Cancer Institute (NCI)Brief Summary: This phase Ib trial studies the side effects of nivolumab and to see how well…
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A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled Study of Evobrutinib Compared With Teriflunomide, in Participants With Relapsing Multiple Sclerosis to Evaluate Efficacy and Safety
Sponsor:Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, GermanyBrief Summary: The study is to evaluate the efficacy…
Feasibility of the Multiple Sclerosis Performance Test for Assessment of Functional Performance Measures in Patients With Multiple Sclerosis
Sponsor:BiogenBrief Summary: The primary objective is to evaluate the feasibility of the Multiple Sclerosis Performance Test (MSPT) in a clinical…
A Single-arm, Prospective, Multicentre, Open-label Study to Evaluate Ofatumumab Treatment Effectiveness and Patient Reported Outcomes in Patients With Relapsing Multiple Sclerosis Transitioning From Dimethyl Fumarate or Fingolimod Therapy
Sponsor:Novartis PharmaceuticalsBrief Summary: The open label study to evaluate effectiveness of treatment with ofatumumab in patients transitioning from commonly used…
A Phase I Study of NeuroVax™, a Novel Therapeutic TCR Peptide Vaccine for Pediatric Multiple Sclerosis
Sponsor:Immune Response BioPharma, Inc.Brief Summary: A Phase I Study of NeuroVax™, a Novel Therapeutic TCR Peptide Vaccine for Pediatric Multiple…
Cladribine Tablets: Observational Evaluation of Effectiveness and Patient-Reported Outcomes (PROs) in Suboptimally Controlled Patients Previously Taking Oral or Infusion Disease-Modifying Drugs (DMDs) for Relapsing Forms of Multiple Sclerosis (RMS) (MASTER-2)
Sponsor:EMD Serono Research & Development Institute, Inc.Brief Summary: To evaluate the effectiveness and safety of cladribine tablets in participants with…
An Open-Label, Multicenter Study to Assess Disease Activity and Biomarkers of Neuronal Damage in Minority Patients With Relapsing Multiple Sclerosis Receiving Treatment With Ocrelizumab
Sponsor:Genentech, Inc.Brief Summary: This is an open-label, multicenter study that includes a main study for all participants enrolled and an…
Brain Health Registry
Sponsor:University of California, San FranciscoBrief Summary: The overall goal of this project is to identify, assess and longitudinally monitor subjects…
Cladribine Tablets: Observational Evaluation of Effectiveness and Patient-Reported Outcomes (PROs) in Suboptimally Controlled Patients Previously Taking Injectable Disease-Modifying Drugs (DMDs) for Relapsing Forms of Multiple Sclerosis (RMS) (CLICK-MS)
Sponsor:EMD Serono Research & Development Institute, Inc.Brief Summary: To evaluate the effectiveness and safety of cladribine tablets in participants with…
Monoclonal Antibodies in Mothers’ Milk and Infants: Ocrelizumab in Breastmilk
Sponsor:University of California, San FranciscoBrief Summary: The goal of the current project is to measure the levels of ocrelizumab in…
