Brain Health Registry
Sponsor:University of California, San FranciscoBrief Summary: The overall goal of this project is to identify, assess and longitudinally monitor subjects…
[searchandfilter fields="search,category" post_types="post"]
Cladribine Tablets: Observational Evaluation of Effectiveness and Patient-Reported Outcomes (PROs) in Suboptimally Controlled Patients Previously Taking Injectable Disease-Modifying Drugs (DMDs) for Relapsing Forms of Multiple Sclerosis (RMS) (CLICK-MS)
Sponsor:EMD Serono Research & Development Institute, Inc.Brief Summary: To evaluate the effectiveness and safety of cladribine tablets in participants with…
Monoclonal Antibodies in Mothers’ Milk and Infants: Ocrelizumab in Breastmilk
Sponsor:University of California, San FranciscoBrief Summary: The goal of the current project is to measure the levels of ocrelizumab in…
A Randomized, Double-Blind, Parallel-Group, Placebo Controlled Trial to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis
Sponsor:University of California, San FranciscoBrief Summary: The main purpose of this study is to assess clemastine as a remyelinating agent…
An Open-Label, Randomized, Multicenter, Active-Controlled, Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 in Pediatric Subjects Aged 10 to Less Than 18 Years for the Treatment of Relapsing-Remitting Multiple Sclerosis, With Optional Open-Label Extension
Sponsor:BiogenBrief Summary: This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple…
Exploratory Study of Entire-body PET Scans for Multiple Sclerosis
Sponsor:Brain Health AllianceBrief Summary: To evaluate whether an entire-body positron emission tomography (PET) scanner can be exploited to improve evaluation,…
International Deprexis Trial in Multiple Sclerosis (IDEMS) – a Multicenter Randomized Controlled Trial
Sponsor:Charite University, Berlin, GermanyBrief Summary: This is an international, multicenter, randomized controlled trial of an internet-based CBT intervention for depression…
A Phase II Randomized, Double-Blind, Parallel-Group, Placebo Controlled Delayed-Start Trial to Assess the Efficacy, Safety, and Tolerability of Bazedoxifene Acetate (BZA) as a Remyelinating Agent in Patients With Multiple Sclerosis
Sponsor:Riley Bove, MDBrief Summary: The primary goal of this study is to assess the efficacy of bazedoxifene (BZA) as remyelinating…
A Phase 3, Randomized, Double-blind, Efficacy and Safety Study Comparing SAR442168 to Placebo in Participants With Primary Progressive Multiple Sclerosis (PERSEUS)
Sponsor:SanofiBrief Summary: Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive…
Teriflunomide Pregnancy Outcome Exposure Registry: An OTIS Autoimmune Diseases in Pregnancy Project
Sponsor:SanofiBrief Summary: Primary Objective: To evaluate any potential increase in the risk of major birth defects, in the first year…
