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A Dyadic Sleep Intervention for Alzheimer’s Disease Patients and Their Caregivers


Brief Summary:

Studies consistently show the negative health impact of sleep problems in both Alzheimer’s
disease (AD) patients and their caregivers. However, only a few sleep interventions have been
conducted for AD patients or their caregivers in community settings and none have addressed
both members of the dyad concurrently. To fill these gaps, this study aims to develop a sleep
intervention program specifically tailored for AD patient/caregiver dyads who both experience
sleep difficulties.


Inclusion Criteria for Alzheimer’s disease (AD) patients:

– AD diagnosis OR probable or possible AD as documented in electronic medical record,
which includes Mini Mental State Exam score >12 (indicating mild to moderate severity
of AD) and neuroimaging evidence

– Community-dwelling

– >1 sleep problem >3x/week on the Neuropsychiatric Inventory Nighttime Behavior Scale

– Aged >60 years

– Able to ambulate with or without assistive device

– Have an eligible caregiver (see below)

Inclusion Criteria for caregivers:

– Live with an eligible patient

– Aged >21 years

– Have regularly assisted patient with >1 of 6 basic activities of daily living (ADLs)
(i.e., bathing, dressing, toileting, transfers, continence, feeding) or >1 of 8
Instrumental ADL (IADLs) (i.e., using the telephone, shopping, preparing meals,
housekeeping, laundry, transportation, taking medicine, managing money) for the past 6

– Pittsburgh Sleep Quality Index (PSQI) total score >5

– Montreal Cognitive Assessment (MoCA) score >= 23

– Can communicate in English

Exclusion Criteria:

– If AD patient is bed bound


  • University of California Los Angeles, Los Angeles, California, United States, 90095
  • Veterans Affairs Greater Los Angeles Healthcare System, North Hills, California, United States, 91343
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